Vinyl Chloride and U.S. EPA Research

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منابع مشابه

EPA programs of vinyl chloride monitoring in ambient air.

Before development of an emission standard for vinyl chloride, the Environmental Protection Agency (EPA) conducted three programs to measure vinyl chloride (VC) concentrations in air around plants which either manufacture VC or use it. A brief monitoring survey conducted by EPA Regional Offices found VC in ambient air around poly(vinyl chloride) (PVC) production plants. As a consequence of this...

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Worker exposure to vinyl chloride and poly(vinyl chloride).

The National Institute for Occupational Safety and Health (NIOSH) in early 1974 began industrial hygiene studies of vinyl chloride exposed workers. Three VC monomer plants, three VC polymerization plants, and seven PVC fabrication plants were surveyed. V polymerization plant workers and workers in one job category in VC monomer plants were exposed to average levels above 1 ppm. The highest aver...

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Vinyl chloride Toxicological overview

 Vinyl chloride is readily and rapidly absorbed via inhalation, ingestion and through the skin  At room temperature vinyl chloride is a gas, so inhalation is the major route exposure  Following absorption, it is distributed through the body, with the highest concentrations found in the liver and kidneys, followed by the lungs and spleen  Vinyl chloride is mainly metabolised in the liver int...

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Vinyl Chloride General information

 Toxic by all routes of exposure – inhalation, ingestion, skin contact  Carcinogenic in humans  Inhalation of vinyl chloride causes coughing, wheezing and breathlessness, headache, ataxia, drowsiness and coma  Ingestion of vinyl chloride causes nausea, vomiting, diarrhoea, abdominal pain, and haematemesis may occur.  Skin contact causes irritation, pain, burns and contact dermatitis. Rapid...

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Quantitative estimated exposure to vinyl chloride and risk of angiosarcoma of the liver and hepatocellular cancer in the US industry-wide vinyl chloride cohort: mortality update through 2013

OBJECTIVE To evaluate mortality risks of angiosarcoma of the liver (ASL), primary hepatocellular carcinoma (HCC) and other cancers among 9951 men employed between 1942 and 1972 at 35 US vinyl chloride (VC) or polyvinyl chloride plants followed for mortality through 31 December 2013. METHODS SMR and time-dependent Cox proportional hazards analyses were used to evaluate mortality risks by cumul...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 2005

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.113-a653